HNE-31903 Randomised Controlled Trials: design and analysis (DL)

Course

Credits 3.00

Language of instruction:

English

Assumed knowledge on:

DL-introduction in analytical epidemiology; DL-integration of evidence 1

Continuation courses:

The DL-MSc-specializations have a fixed schedule during the pilot-phase

Contents:

Note: this course is NOT taught in the 17/18 academic year.
Note: This course has a maximum number of participants. The deadline for registration is one week earlier than usual. See Academic Year.(http://www.wageningenur.nl/en/Education-Programmes/Current-Students/Agenda-Calendar-Academic-Year.htm) -> Registration for Courses.
Note: The period mentioned below is the period in which this course starts. For the exact academic weeks see the courseplanning on www.wur.eu/schedule.

This course focuses on the methodological issues in designing an experimental study: how to obtain an appropriate sample size and how to perform statistical analysis of data derived from randomized controlled trials.

Learning outcomes:

After successful completion of this course students are expected to be able to: - formulate a good research question;
- evaluate the validity and precision of a parallel arm post-test only, parallel arm pre-test post-test, and cross-over design;
- perform appropriate sample size calculations for different study designs;
- choose and conduct the appropriate method of data analysis of randomized controlled trials, given the study design and type of variables.

Activities:

Studying knowledge clips, studying e-modules, individual assignment, and individual assignment with peer-review.

Examination:

Remote proctored written exam (70%), Assignments during the course (30%). Both need a minimum mark of 5.5 to pass the course.

Literature:

Petrie & Sabin, Medical statistics at a glance, chapters 9, 13, 20, 21, 22, 24, 41.