PHP-30806 Molecular Aspects of Bio-interactions
Vak
Studiepunten 6.00
| Onderwijstype | Contacturen |
| Lectures | 20 |
| Practical intensively supervised | 80 |
| Problem-based learning | 20 |
| Self-study |
| Course coordinator(s) | dr. JAL van Kan |
| Lecturer(s) | dr. JAL van Kan |
| prof. dr. M Dicke | |
| dr. G Smant | |
| dr. ir. JWM van Lent | |
| Examiner(s) | prof. dr. ir. PJGM de Wit |
Language of instruction:
English
Contents:
The course aims to provide insights into the molecular basis of the interactions of plants and their attackers (viruses, insects, nematodes, microorganisms) and describes how these insights may be exploited in development of novel strategies for control and containment of attackers. The strategies are discussed by which the attackers invade the host plant and reproduce in or on the host tissue, with emphasis on gene and protein function in these processes. The repertoire of defense mechanisms that plants possess to (directly or indirectly) ward off attackers is described. It is discussed which mechanisms may be effective against particular types of attackers, either locally or systemically. The structural and functional similarities among plant resistance genes in relation to their specificity are discussed at the level of DNA sequence and protein structure. An important aspect of defense consists of signalling processes within an individual plant and to its neighbours. The role of individual signal transduction pathways and the cross-talk among pathways are discussed. Finally it is discussed how the fundamental molecular knowledge on these biological processes is exploited for improving control measures, by novel non-toxic chemicals or genetic modification. Experiments in the practical course illustrate aspects of the theory.
Activities:
Lectures, practical course.
Examination:
On the basis of a written exam (50%), the experimental skills and quality of the report of the practical (50%). The mark for the exam must be sufficient.
Literature:
Provided by the lecturers during the course.