SSB-20806 iBiosystems


Studiepunten 6.00

Group work2
Course coordinator(s)dr. PJ Schaap
dr. I Sanchez Andrea
Lecturer(s)prof. dr. SC de Vries
prof. dr. D Weijers
dr. PJ Schaap
MSc JJ Koehorst
dr. I Sanchez Andrea
Examiner(s)prof. dr. SC de Vries
dr. PJ Schaap

Language of instruction:


Assumed knowledge on:

BIC-10306 Practical Biological Chemistry; CBI-10306 Cell Biology; MIB-10306 Microbiology & Biochemistry

Continuation courses:

Bioinformation Technology, Molecular Systems Biology


In this era of genomics, computational analysis has become an integral part of normal 'wet-lab' routines. In this course we introduce the 'Moist-lab': a new style of research where hands-on wet-lab experiments and hands on computational predictions are combined in an integrative wet-dry cycle to study genotype-phenotype relationships in prokaryotes and simple eukaryotes. By doing wet-lab experiments, we will in this course determine interesting biochemical and physiological properties from these organisms and compare them with genotypic properties that we will predict hands-on from genome data.
During the course a digital lab journal will be used to keep track of the entire process, enabling to do your research in FAIR way (Findable, Accessible, Interoperable, Reusable).

Learning outcomes:

After successful completion of this course students are expected to be able to:
- analyze predictions of commonly used computational tools in the field of genomics;
- analyze and design iterative wet-dry lab experiments;
- document experimental procedures and store data and data provenance in a FAIR way;
- communicate research findings through a scientific report.


This is hands-on group work (wet-lab 4; dry-lab 2 persons). Student are expected to: attend lectures; perform laboratory and computational experiments; maintain a digital lab journal; write a digital lab report.


The final mark is based on; a written exam that contains a number of multiple-choice questions (approx. one-third on the experimental part, two-third on the computational part) (2/5), a concise digital lab journal (1/5) and a digital lab report (2/5). To pass the exam, the mark for each part should be at least 5,0. To pass the course, the combined mark should be at least 5.5.


Guidelines and protocols will be supplied in Brightspace.

Keuze voor: BBTBiotechnologyBSc2MO
Keuze voor: WUSYBBSc Minor Systems Biology2MO