PBR-34303 Genomics and Bioinformatics

Vak

Studiepunten 3.00

OnderwijstypeContacturen
Lecture0
Tutorial0
Independent study0
Distance group work0
E-learning material0
Course coordinator(s)dr. CWB Bachem
Lecturer(s)dr. ir. HJ van Eck
dr. CWB Bachem
JE Risse
Examiner(s)dr. ir. HJ van Eck
JE Risse
dr. CWB Bachem

Language of instruction:

EN

Assumed knowledge on:

Basic knowledge of Molecular Biology and Genetics. It is necessary to have followed an online course at Wageningen University before, or the special Onboarding course for distance learning. To get access to the Onboarding course, send an email to: onboarding.wur@wur.nl.

Contents:

Note 1:  This course can not be combined in an individual programme with BIF20306 Introduction to Bioinformatics.

Note 2: This course has a maximum number of participants. The deadline for registration is one week earlier than usual. See Academic Year.(http://www.wageningenur.nl/en/Education-Programmes/Current-Students/Agenda-Calendar-Academic-Year.htm) -> Registration for Courses.
Note 3: The period mentioned below is the period in which this course starts. For the exact academic weeks see the courseplanning on www.wur.eu/schedule.
Note 4: This course is offered online and it takes about 20 hours to complete the weekly task. There are assignments with deadlines and non-synchronous interaction with teachers and fellow students.  


Genomics is a new area of research that relates to holistic study of the genome a the gene, transcript, protein and metabolite levels. Due to the large amounts of data involved in this study computer tools are extensively used. During the course we will present basic concepts genomics and introduce students to the problems of dealing with and understanding these large datasets. We will discuss the basic architecture of the genome and the implications for genome evolution. We will also deal with the structural and functional aspects of genomics from gene through to metabolites. The course will help the students to analyse and understand the links and relationships between genes and their various products. The course will comprise information packages in the form of knowledge clips and these will be combined with a large number of exercises where the knowledge provided will be applied to practical bioinformatics problems.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- understand the organisation of plant genomes and how these evolved;
- explain the connections between gene, transcript, protein and metabolite;
- understand the technologies that generate the various genomics data sets;
- analyse genomics data and retrieve biologically significant information from it;
- understand the dependence and interactions between the different functional genomics levels;
- integrate information from genes to pathways to networks at an organism level;
- understand and debate the potential role of genomics in a wider societal and cultural setting.

Activities:

- read and understand the set texts and literature provided in the course;
- watch and study the knowledge clips and other learning material;
- follow the computer tutorials;
- carry out the exercises and report the results;
- participate in on-line debates and discussions;
- carry out and submit assignments.

Examination:

There are around 6 exercises during the course, each with online quizzes comprising about 10 questions each. Marks for these tests will be included for the overall mark, accounting for 30% of the overall grade. In addition, a written assignment report (50% of the overall grade) and oral presentation (20% of the overall grade) form part of the evaluation. The presentation is peer-group evaluated. Each of the three evaluation components needs at least a 5.5 to pass the course.

Literature:

Information will be primarily provided in the online course material. Other information sources will be actively retrieved from the providers of internet tools that will be used throughout the course.

OpleidingFaseSpecialisatiePeriode
Verplicht voor: MPSDLSpec. Plant Breeding DLMSc3DL