HAP-32303 Essentials of Nutritional Physiology


Studiepunten 3.00

Knowledge clip0
Independent study0
E-learning material0
Course coordinator(s)dr. S Grefte
dr. C Carmone
Lecturer(s)dr. S Grefte
dr. ir. EM van Schothorst
dr. C Carmone
Examiner(s)dr. ir. EM van Schothorst
dr. S Grefte

Language of instruction:


Assumed knowledge on:

Basic knowledge on nomenclature and chemical structures of macro-nutrients (also see chapters 1, 4, 5, and 6 of Course book Crash Course Metabolism and Nutrition Updated Edition (4th Edition))


Note 1: The period mentioned below is the period in which this course starts. For the exact academic weeks see the courseplanning on www.wur.eu/schedule.

Note 2: This course can not be combined with the curricular course HAP-30306 Nutritional Physiology.

Aim: The sources of energy in our diet for the human body are carbohydrates, lipids, and proteins. The focus of this course is on metabolism of these macro-nutrients to provide cellular energy. We start in the first week by discussing the processes involved in mitochondrial ATP production. In the second week we discuss the details and purpose of the biochemical pathways involved in carbohydrate metabolism followed by protein metabolism. The focus of the third week is on fat metabolism. Via several individual assignments you will apply and integrate the knowledge you acquired to become more familiar with the biochemical pathways.
Relevance: The design and evaluation of epidemiological observational and experimental nutritional studies were introduced previously in other courses within your DL-study program. However, a basic understanding of carbohydrate, lipid and protein metabolism is critical to 1) decide which strategies will be used to clinically assess metabolic and nutritional disorders and 2) how to interpret the data obtained.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- describe the process of mitochondrial ATP production;
- describe the regulation of metabolism during fasting and feeding;
- explain the differences between glucose, lipid, and protein metabolism;
- analyse the amount of energy derived from glucose, protein and fat intake;
- integrate the biochemical pathways involved in carbohydrate, protein and lipid metabolism;


Most e-learning materials, activities, and feedback will be provided asynchronously and consists of:
- textual explanations, animations, and quizzes to obtain the basic knowledge;
- continuous individual assignments;
- individual assignments with a deadline resulting in a product (metabolic map, calculation exercises);
- an e-forum to discuss problems, ask questions, etc.


3x individual assignments (accounts for 30% of the final grade).

Online combined written and multiple choice exam (accounts for 70% of the final grade, with a minimum grade of 5.0).

The minimal required mark for the online combined written and multiple choice exam is a 5.

The grades of the individual assignments have no expiration date.


Crash Course Metabolism and Nutrition Updated Edition (4th Edition); Amber Appleton, Olivia Vanbergen, and Daniel Horton-Szar; Elsevier ISBN 978-0-7234-3853-3 (obligatory course material).

Verplicht voor: MNHDLNutritional Epidemiology and Public HealthMSc3DL