ADP-20306 Immunology and Thermoregulation


Studiepunten 6.00

Individual Paper1
Course coordinator(s)dr. ir. H van den Brand
Lecturer(s)dr. ir. HK Parmentier
dr. A Lammers
dr. ir. H van den Brand
Examiner(s)dr. ir. HK Parmentier
dr. ir. H van den Brand

Language of instruction:


Mandatory knowledge:

ZSS06100 Laboratory Safety

Assumed knowledge on:

Cell biology, Human and Animal Biology I and II


Within certain limits, animals can compensate environmental stress and changes in the environment (homeostasis). Homeostasis is the basis of the adaptive capacity of an individual. The amount and the predictability of stress determine how much adaptive capacity is used to survive, and what is available for health, disease resistance, welfare, and (re) production. This is true both for abiotic as well as biotic loads of an individual. This introduction course deals with the various mechanisms through which environmental factors influence the animal (as far as known), and the consequences of the effects on (infectious) disease resistance, and the capacity to (re)produce. The effects of environmental factors (temperature, light, dust, air and climate) and their effects on terrestrial and aquatic animals will be discussed. This should contribute to obtain knowledge on the basal husbandry demands of animals. This course is based on the disciplines of immunology, environmental physiology and thermoregulation of animals as parameters of health and production.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- explain how human beings and animals regulate their body temperature;
- explain the basic processes and basic functions of the immune system;
- explain how environmental factors, animal factors and climate factors, including their interactions affect thermoregulation and immune response;
- recognize the role of the immune system in preventing or combatting (infectious) diseases, and maintenance of health;
- discuss which interaction(s) between thermoregulatory processes and immune mechanisms underlie disease and disorders;
- exemplify the adaptive capacity of animals under changing conditions.


The course consists of approximately 40 lecture hours and 5 mornings or afternoons practical intensive.
During these practicals, a number of simple immunological techniques will be practised, next to measurements and calculations with animals kept in climate respiration chambers. Results of the practicals must be reported in an abstract.


- written exam with open and multiple choice questions (90%), each of the two parts: thermoregulation (45%) and immunology (45%) requires a minimum of 5.5
- Individual essay (10%), minimum grade 5.5.


Handouts (English) are available during the course.
A reader for Thermoregulation (obligatory)
I. Tizard. (2012). Veterinary Immunology, publisher Elsevier (Saunders), 10th edition, ISBN 978-0-03235-2349-3 (recommended)

Verplicht voor: BASAnimal SciencesBSc2AF
Verplicht voor: WUANSBSc Minor Animal Sciences2AF