HNH-32403 Observational Designs and Assessment of Validity


Studiepunten 3.00

Knowledge clip0
Individual Paper0
Independent study0
E-learning material0
Course coordinator(s)dr. ir. MC Busstra
Lecturer(s)dr. ir. MC Busstra
prof. dr. JM Geleijnse
prof. dr. ir. E Kampman
Examiner(s)prof. dr. ir. E Kampman
dr. ir. MC Busstra

Language of instruction:


Assumed knowledge on:

Either the online courses: Introduction Descriptive Epidemiology and Public Health (HNH-28303); Introduction to Analytical Epidemiology and Public Health (HNH-28803); Integration of Evidence I (HNH-30403), or the on campus course Introduction to Epidemiology and Public Health (HNH-24806)


Note: This online course largely overlaps with the course HNH-31006 Study designs and interpretation in Epidemiology and Public Health. Therefore, this course can not be combined in an individual programme with HNH-31006: Study design and Interpretation in Epidemiology and Public Health.

In this course, you will learn to evaluate the validity of results obtained from observational research. You will deepen your understanding of selection error, information error, confounding, and effect measure modification. You will also learn more about observational design variants: nested case-control and case-cohort designs.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- understand and explain the characteristics of observational study designs (i.e., cohort study, case-control study, nested case-control study, case-cohort study);
- understand and explain potential methodological threats with respect to internal and external validity (i.e., selection bias, information bias, confounding, effect measure modification) in these designs;
- critically evaluate studies used in epidemiology, taking methodological considerations into account.


E-modules, knowledge clips, online group discussion, individual assignment (including producing video).


Remote proctored written exam with open and closed questions (70%), several individual and/or group assignments during the course (30%). For both a minimum mark of 5.5 is needed to pass.


Penny Webb, Chris Bain, Andrew Page. Essential Epidemiology. Cambridge University Press, 2nd or 3rd ed.

Verplicht voor: MNHDLNutritional Epidemiology and Public HealthMSc1DL