HNE-32403 Observational Designs and Assessment of Validity (DL)


Studiepunten 3.00

Individual Paper
Independent study
Distance Knowledge clip
Distance Tutorial
Distance E-learning material
Course coordinator(s)dr. ir. AM Berendsen
dr. ir. MC Busstra
Lecturer(s)prof. dr. ir. E Kampman
prof. dr. JM Geleijnse
dr. ir. MC Busstra
Examiner(s)prof. dr. ir. E Kampman

Language of instruction:


Assumed knowledge on:

DL-Introduction Descriptive Epidemiology; DL-Introduction to analytical Epidemiology; DL-Integration of Evidence 1

Continuation courses:

The DL-MSc-specializations have a fixed schedule during the pilot-phase


Note: This course has a maximum number of participants. The deadline for registration is one week earlier than usual. See Academic Year.( -> Registration for Courses.
Note: The period mentioned below is the period in which this course starts. For the exact academic weeks see the courseplanning on

This course focuses on the aspects one has to take into account when wanting to evaluate the validity of observational studies.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- understand and explain the characteristics of observational study designs (i.e., cohort study, case-control study, nested case-control study, case-cohort study);
- understand and explain potential methodological threats with respect to internal and external validity (i.e., selection bias, information bias, confounding, effect measure modification) in these designs;
- critically evaluate studies used in epidemiology, taking methodological considerations into account.


E-modules, knowledge clips, online group discussion, individual assignment (including producing video).


remote proctored written exam (70%), assignments during the course (30%). For both a minimum mark of 5.5 is needed to pass.


Webb & Bain, Essential Epidemiology, 2nd ed.

Verplicht voor: MNHNutrition and HealthMScE: Nutritional Epidemiology and Public Health1DL