|Course coordinator(s)||dr. ir. EM van Schothorst|
|Lecturer(s)||dr. ir. EM van Schothorst|
|Examiner(s)||dr. ir. EM van Schothorst|
|prof. dr. ir. J Keijer|
Language of instruction:
Assumed knowledge on:
EZO-10306 Human and Animal Biology I and HAP-20306 Human and Animal Biology, part 2, or HAP-10306 Principles of Human Physiology and HAP-21303 Integrated Human Physiology.
This course is focussed on the physiological utilisation of dietary macro-nutrients (carbohydrates, fat and protein) and discusses their flow from oral intake to their utilisation and/or excretion under various physiological conditions as maintenance, production, physical activity, stress etc. Metabolism is discussed as an interface between 'Nutritional Input' and 'Physiological Output' of the body.
This course discusses the main biochemical processes involved in digestion, absorption and metabolism of macro-nutrients.
Special attention will be paid to potential constraints for proper physiological functioning of the body.
The intensity of energy metabolism might have adverse effects on the ability to maintain the body temperature depending on the environmental conditions (thermo-neutral zone, comfort zone). Within protein metabolism there may be a friction between the efficiency of protein utilization for maintenance, protein deposition and the ability to cope with stress conditions as far as mediated by protein turnover.
With regard to (semi)-quantitative aspects relevant for nutritional physiology specific assignments will be discussed. In a practical part students will be allowed to study aspects of digestion, absorption and metabolism in both "in vivo and in vitro" experiments.
After the course the student is expected to be able to:
- describe and explain general digestive functions and main metabolic pathways;
- predict settings of metabolism based on nutritional input and physiological output;
- estimate changes in energetic efficiencies in relation to changing conditions;
- judge physiological conditions in terms of constraints for homeostatic control.
The course encloses 36 lectures, 9 hours for assignments, and a practical (24 hours).
Examination is based on written test with multiple choice questions.
Several chapters of Textbook:
David A Bender. Introduction to Nutrition and Metabolism. 5th ed. 2014. CRC Press, Taylor & Francis Group, Boca Raton, USA. ISBN 978-1-4665-7224-9.
The main course material, including handouts of lecture slides, will be available on Blackboard.