BIP-32803 Biophysical Imaging
Course
Credits 3.00
Teaching method | Contact hours |
Practical | 64 |
Course coordinator(s) | dr. H Van As |
Lecturer(s) | JR Krug |
dr. JC Hohlbein | |
dr. AN Bader | |
dr. E Wientjes | |
dr. H Van As | |
dr. ir. JM Kleijn | |
C Terenzi PhD | |
dr. TE Kodger | |
N de Lange | |
KJA Martens | |
Examiner(s) | dr. H Van As |
Language of instruction:
English
Assumed knowledge on:
Analitical Chemistry or Spectroscopy.
Contents:
Note: This course has a maximum number of participants. The deadline for registration is one week earlier than usual.
See Academic Year.(http://www.wur.nl/en/Education-Programmes/Current-Students/Agenda-Calendar-Academic-Year.htm) -> Registration for Courses.
Imaging techniques play an important role in biophysical research. In this course the principles of spectroscopic microscopy [confocal laser scanning microscopy, fluorescence (life time) and NMR imaging (MRI), ultra-microscopy (atomic force microscopy) will be presented. In addition, principles of image processing and analysis, manipulation and interpretation of two- and three dimensional datasets will be treated. The techniques will be illustrated by applications on biological processes, structure-function relationship, assembly and complexation of macro-molecules and the determination of the structure of surfaces.
Learning outcomes:
After successful completion of this course students are expected to be able to:
- understand the available techniques for imaging of biological systems,
- make the proper choice and use of the techniques in practical biophysical research.
Activities:
- study syllabus;
- solve exercises, do practical experiments;
- write a report;
- use ICT for analysis of results and present results.
Examination:
This course will be judged based on active participation, understanding, presentation, results and written reports as follows:
- execution of problems and experiments (10%);
- understanding of the methods (20%);
- execution of the reports (50%);
- presentation of the results and conclusions of the projects (20%).
In these elements the MRI part counts for 50%, the FLIM/CLSM and the AFM parts each for 25%.
Literature:
Syllabus and manual for practicals will be available before the start of the course.
Programme | Phase | Specialization | Period | ||
---|---|---|---|---|---|
Restricted Optional for: | MBT | Biotechnology | MSc | D: Process Technology | 4MO |
MML | Molecular Life Sciences | MSc | 4MO |