GEN-30806 Population and Quantitative Genetics

Course

Credits 6.00

Teaching methodContact hours
Lectures24
Tutorial51
Course coordinator(s)dr. DK Aanen
Lecturer(s)prof. dr. FA van Eeuwijk
dr. ir. P Bijma
dr. WF van Hooft
dr. DK Aanen
dr. M Malosetti
dr. AP Kause
Examiner(s)dr. DK Aanen

Language of instruction:

Dutch and/or English

Assumed knowledge on:

MAT-15303+MAT-15403

Contents:

This course explains the phenotypic, genetic and molecular evolution of populations under natural and artificial selection. Topics covered are: genetic variation and the evolution of gene frequency; multi-locus genetics and linkage disequilibrium; the effects of mutation, selection, drift, migration and inbreeding in relation to the population structure; polygenic inheritance, heritability, and the evolution of quantitative traits; genotype by environment interaction and environmental sensitivity; conservation genetics and the genetic management of small populations, and the interpretation of results from genetic analyses of populations.

Learning outcomes:

The student is able to apply population and quantitative genetic concepts to: - problems related to the genetic dynamics of natural, captive and artificially selected populations;
- problems related to the erosion of genetic diversity and methods for genetic conservation of populations;
- infer consequences of population history for the current genetic characteristics of populations, and to infer population history from current data.

Activities:

Lectures and tutorials; the tutorials will be devoted to problem solving, data analysis (including ICT), and case studies

Examination:

Written exam. The score on the tutorials is part of the final mark.

Literature:

The book A Primer of Population Genetics, Daniel L. Hartl. 3rd ed. (Sinauer Assoc.) will be used. Additional lecture notes on selected topics will be provided also.

ProgrammePhaseSpecializationPeriod
Restricted Optional for: MBIBiologyMScD: Ecology6WD
MASAnimal SciencesMScA: Animal Breeding and Genetics6WD
MPSPlant SciencesMScD: Plant Breeding and Genetic Resources6WD
MPSPlant SciencesMScD: Plant Breeding and Genetic Resources6WD