EZO-31804 Laboratory Animal Science Course

Vak code vorig jaar: (YAS-30304)


Studiepunten 4.00

Practical intensively supervised17
Course coordinator(s)A Terlouw
Lecturer(s)drs. RJM Steenmans a.o.
Examiner(s)drs. RJM Steenmans

Language of instruction:


Assumed knowledge on:

The applicant shall have acquired knowledge on the basic subjects of biology up to 18.75 credits (= 500 study hours) including at least 7.5 credits on anatomy/zoology and 7.5 credits on physiology. These terms of admission are in accordance with the formal requirements of the Dutch responsible authority. Successfully passing e.g. Human and Animal Biology I (EZO-10306) and Human and Animal Biology II (HAP-20306) and Vertebrate structure and function (EZO-31306) meets these requirements.


Dutch Law requires that animal experimentation is carried out by properly trained people. For researchers this implies that, on top of a biological or biomedical university degree, a so-called Article 9 certificate is needed. The Laboratory Animal Science (LAS) Course given in Wageningen leads to such a certificate, when the course is fully attended (two to three weeks) and the exam is successfully completed. The LAS course entails scientific, ethical and practical aspects of animal experimentation. The main purpose of the course is to enhance a positive attitude towards animal needs and well-being. As to optimize the exchange of information, but more importantly thoughts and opinions, the course is given entirely in Dutch.

Learning outcomes:

After successful completion of this course students are expected to:
- have a critical and analytical attitude towards the scientific knowledge underlying Laboratory Animal Science related activities;
- be able to assess their scientifically based knowledge and skills;
- be familiar with legislation concerning the use of laboratory animals;
- knows about basic principles, which guide towards the ethical judge ment of animal experiments;
- know about the possibilities and limitations of alternative techniques;
- have knowledge of the requirements of laboratory animals with respect to housing, nutrition and care;
- possess the necessary knowledge for responsible animal handling and also obtained some practical experience in this respect;
- have taken note of the different methods for the collection of body fluids;
- have taken note of a number of other frequently used experimental techniques (amongst others cannulation, insertion of catheters);
- possess the knowledge to recognize pain as well as discomfort in laboratory animals and to define humane end points;
- have knowledge of the most important methods of anesthesia, analgesia and euthanasia, which can be used in various laboratory animal species;
- have knowledge of the possible impact of environmental and procedural factors on experimental results;
- have knowledge of the importance of hygienic measures and barrier systems;
- have knowledge of the impact of diseases in laboratory animals on the experimental approach and knows about possible health monitoring;
- know about the specific demands that are necessary for a correct preparation and performance of animal experimental techniques and research;
- know the possibilities that statistics can offer to optimize the use of laboratory animals.


- compulsory participation to lectures and practical class
- active participation to project learning and literature study.


75 % written examination, 25 % project learning and literature study. The exam must be passed with 5.5 or higher.


- Zutphen van L.M. (2009) Handboek Proefdierkunde; 5 editie; Reed business;
- a study guide, synopsis of lecturers, handouts of recent papers and handouts for laboratory class work.

Keuze voor: MBIBiologyMSc1AF, 6WD
MASAnimal SciencesMSc1AF, 6WD
MNHNutrition and HealthMScC: Molecular Nutrition and Toxicology1AF, 6WD