EZO-22306 Developmental Biology of Plants and Animals


Studiepunten 6.00

Practical extensively supervised48
Course coordinator(s)dr. ir. S Kranenbarg
Lecturer(s)prof. dr. T Bisseling
dr. ir. S Kranenbarg
Examiner(s)prof. dr. T Bisseling
dr. ir. S Kranenbarg

Language of instruction:

Dutch and/or English

Assumed knowledge on:

Fundamentals of genetics and molecular biology (GEN-11806); Structure and function of plants (PPH-10806); Human and animal biology I (EZO-10306); Reproduction of plants (PCB-10803; Modeling biological systems (PPS-21306); Mechanisms of development (MOB-20803); Practical biological chemistry (BIC-10306)

Continuation courses:

Developmental biology of animals (EZO-30306); Molecular dDevelopmental biology of animals (EZO-30306); Molecular development (MOB-31303); Regulation of plant development (MOB-30806)evelopment (MOB-31303); Regulation of plant development (MOB-30806)


The course offers a systems biology approach to the development of plants and animals. This approach bridges the gap between the traditional systems biology at the molecular and cellular levels and the integrative models at the ecological level. The developing organism is considered a system that needs to function and survive in its environment. To deepen our understanding of these systems, we will work with advanced - often mathematical - models. The content of each week is centered around a theme and integrates aspects of both plant and animal development. During the last week of the course, the students will integrate and expand their knowledge by preparing a presentation and leading a discussion. The central themes of the weeks are:
- multicellular development;
- gene networks;
- gradient formation;
- pattern formation;
- polarity;
- regeneration.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- give examples of how a systems biology approach to developmental biology is essential to a proper understanding of the field;
- interpret and apply the quantitative approaches provided for the analysis of the five phenomena presented in the course (multicellular development, gene networks, gradient formation, pattern formation, polarity);
- appraise the value of a scientific paper and deduce its contribution to the understanding of particular phenomenon;
- analyse a number of scientific papers on regeneration and combine their content with the content of the course into a coherent presentation;
- exemplify similarities and differences between plant and animal development from a conceptual point of view.


- lectures;
- computer cases;
- literature study.


Written examination.


A manual will be available.

Verplicht voor: BBIBiologyBScB: Organismal and Developmental Biology5MO