MIB-10306 Microbiology & Biochemistry

Course

Credits 6.00

Teaching methodContact hours
Lecture36
Tutorial7
Practical26
Course coordinator(s)dr. SWM Kengen
Lecturer(s)dr. SWM Kengen
dr. LMC Nitsch
prof. dr. D Weijers
MSc PGB Puylaert
dr. ir. CPM van Mierlo
prof. dr. SC de Vries
dr. ir. D Sipkema
I Rabbers
Examiner(s)dr. LMC Nitsch
prof. dr. SC de Vries
prof. dr. D Weijers
dr. ir. D Sipkema
dr. ir. CPM van Mierlo
dr. SWM Kengen

Language of instruction:

Dutch (Period 2 and 3-4). English (period 5)

Contents:

Note: This course can not be combined in an individual programme with MIB-11306 Microbiology and Biochemistry for Nutrition and Health.

Genetic, physiological, morphological and ecological aspects of prokaryotes and primitive eukaryotes are addressed. The omnipresence and diversity of microorganisms is the central item.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- explain the importance of the large diversity of microorganisms for development and sustainment of life on earth;
- explain that structure and function of enzymes are a link between chemistry and the living cell, and that biochemical unity underlies biological diversity;
- explain the following basic principles of metabolism of (micro)organisms: manipulation of free energy by enzymes to direct metabolism, importance of oxidation-reduction reactions for extracting energy from organic and inorganic substrates, glycolysis, citric acid cycle and respiratory chain;
- compare the basal metabolism with glucose as a model substrate in (micro)organisms in the presence and absence of external electron acceptors;
- summarize a number of microbial interactions in specific ecosystems;
- exemplify the influence of environmental factors on microbial activity in the cycling of nutrients, like carbon, nitrogen, sulfur and iron;
- practice a set of basic microbial experiments with emphasis on aseptic techniques for transfer and handling of microorganisms;
- enrich and isolate microorganisms under defined environmental conditions.

Activities:

- attend lectures that are supported by 2 textbooks;
- perform several laboratory experiments;
- assess acquired practical knowledge by answering questions, compose a lab journal and give a short presentation.

Examination:

The final mark is based on:
- two written exams, biochemistry (1/3) and microbiology (2/3), with open and multiple choice questions.
- to pass the exam, the mark for each exam should be at least 5.00. To pass the course, the combined mark should be at least 5.50.

Literature:

Textbooks are:
Michael T. Madigan [et.al]. (2018). Brock Biology of Microorganisms. 15th Global edition. Pearson, ISBN 13: 9781292235103.
Jeremy M. Berg; John L. Tymoczko; Lubert Stryer. (2019). Biochemistry. 9th edition. WH Freeman; ISBN: 1319114652
Textbook and practical course handbook are available at the WUR-shop in the Forum.

ProgrammePhaseSpecializationPeriod
Compulsory for: BBIBiologyBSc2AF
BBTBiotechnologyBSc3AF+4AF
BFTFood TechnologyBSc5AF
BESEnvironmental SciencesBSc5AF
BMLMolecular Life SciencesBSc3AF+4AF
Restricted Optional for: BATBiosystems EngineeringBSc2AF, 3AF+4AF