HNH-31903 Randomised Controlled Trials: Design and Analysis (online)

Code last year: (HNE-31903)


Credits 3.00

Teaching methodContact hours
Knowledge clip0
Individual Paper0
Independent study0
E-learning material0
Course coordinator(s)dr. ir. RM Winkels
Lecturer(s)dr. ir. NM de Roos
dr. ir. RM Winkels
Examiner(s)dr. ir. RM Winkels

Language of instruction:


Assumed knowledge on:

Introduction in analytical epidemiology; Integration of evidence I


Note: This course can not be combined in an individual programme with HNH-24306 Methodology Nutrition Reseach.
This course focuses on the methodological issues in designing an experimental study: how to obtain an appropriate sample size and how to perform statistical analysis of data derived from randomized controlled trials.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- formulate a proper research question to be answered using an RCT;
- evaluate the validity and precision of a parallel arm post-test only, parallel arm pre-test post-test, and cross-over design;
- perform appropriate sample size calculations for different study designs;
- choose and conduct the appropriate method of data analysis of randomized controlled trials, given the study design and type of variables.


Studying knowledge clips, studying e-modules, individual assignment, and individual assignment with peer-review.


Remote proctored written exam (70%), Assignments during the course (30%). Both need a minimum mark of 5.5 to pass the course.


Petrie & Sabin, Medical statistics at a glance, chapters 9, 13, 20, 21, 22, 24, 41.

Compulsory for: MNHNutrition and HealthMScE: Nutritional Epidemiology and Public Health4DL