BPE-12806 Bioprocess Engineering Basics BT


Credits 6.00

Teaching methodContact hours
Course coordinator(s)T Haasterecht
I Houthoff
Lecturer(s)dr. ir. MH Vermuë
T Haasterecht
I Houthoff
Examiner(s)T Haasterecht
dr. ir. MH Vermuë

Language of instruction:

NL and/or EN

Assumed knowledge on:


Continuation courses:

BPE-22306 Basic cell factory design, BPE-21306 Bioreactor Design and BPE-20806 Separation Process Design


This course can not be combined in an individual programme with BCT10805 Process Engineering Basics.
This course is the first in a series of process engineering courses. It introduces the basics of design of production and transfer processes which are relevant for biotechnology.The design of the required equipment and the design of an entire biotechnological production process will be based on element, component and energy balances. These balances involve mathematical equations that can be applied to find the required energy or required energy and mass flows for conversion or separation processes. The emphasis in this course is on analyzing and solving relatively simple design problems; optimization of the design and analysis of more complex problems are taught in later courses. The course illustrates how process engineers can contribute to the development of sustainable biotechnological production processes.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- analyse given processes that are relevant for biotechnology and individual process steps that involve mass and energy transfer or production;
- set up element balances, component balances and energy balances that mathematically describe what goes on in a given process;
- apply stoichiometry and use an equilibrium approach in balances to evaluatte the feasibility of individual process steps and to evaluate the feasibility of an entire process chain;
- apply simplified mathematic kinetic models in balances to describe and design conversion processes;
- select and combine the right energy and mass balances  for the design of individual steps in a biotechnological process.


- instruction lectures;
- make assignments;
- a practical case-study;
- writing a report on the practical case-study;
- self study;
- written exam.


Individual assessment based on the case-study report (25%) and written exam (75%).
Both marks must be equal or more then 5.5.


Study guide and book (Doran) are available on the first day of the course.

Compulsory for: BBTBiotechnologyBSc5MO
Restricted Optional for: WUBITBSc Minor Biotechnology5MO