BNT-51306 BioNanoTechnology: Sensors & Devices


Credits 6.00

Teaching methodContact hours
Excursion (one day)8
Course coordinator(s)dr. V Saggiomo
Lecturer(s)prof. dr. AH Velders
dr. V Saggiomo
dr. A Bunschoten
Examiner(s)prof. dr. AH Velders
dr. V Saggiomo

Language of instruction:


Mandatory knowledge:

ZSS06100 Laboratory Safety

Assumed knowledge on:

BNT-50806 Bionanotechnology: an introduction

Continuation courses:

BioNanoTechnology; towards Nanomedicine


Building on the foundations laid in BioNanoTechnology; an Introduction, this course will focus on applications of micro- and nanotechnology in sensors and devices. Sensors and devices are ubiquitously used for detection of various analytes in many different fields spanning from environmental analysis to medical applications and forensics science. This course deals with molecular/chemical aspects of (nano)sensors and their applications, and with the fabrication and use of devices. Various chemical/nano sensor systems will be presented, from colorimetric and fluorescent sensors to the use of NMR for the detection of analytes in water, soil and food. Microfluidics devices will be both explained and fabricated/used in laboratory. In laboratory classes, different devices will be fabricated and tested during this course based on: paper microfluidics, smartphone, 3D printing and microcontroller programming (Arduino, a powerful open source development board). Reading and interpreting scientific literature in the field of sensors and devices will be integral part of the course. State-of-the-art Implementation of sensors in analysis will be explored during an excursion.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- understand analytes, nanomaterials, surface-functionalization, covalent/non-covalent interactions, supramolecular chemistry;
- explain how chemical & physical sensors work, the meaning of limit of detection, signal to noise ratio and control experiments;
- apply UV-Vis absorption/fluorescence and NMR spectrometers for the detection of sensor-analyte interactions;
- use computer image programs for the determination of analytes using chemical sensors and a cellphone and construct a calibration curve for an analyte and use it for its quantitative determination in an unknown sample;
- evaluate flowcharts and algorithms for the fabrication of a device;
- assemble, program and use of Arduino for the fabrication of a device capable of reading chemical sensors. - process and interpret the data from various sensors;
- plan, design and invent new application for Arduino sensors;
- read and interpret scientific literature in the field of (bio)nanotechnology, sensors and devices.


Attend lectures, study the course material (Book/ handouts / articles) and make exercises. Perform illustrative experiments and write a report in which the relation between theory, laboratory classes and implementation in research institutes is adequately described.


The final mark is determined by:

- the written exam (50%);

- the performance during the laboratory classes (10%);

- and the quality of the report on the experiments, literature assignments and excursions (40%).

The marks for performance during the laboratory classes and the report on the experiments must be 5 or higher.


Mel I. Mendelson. (2013). Learning Bio-Micro-Nanotechnology. 611p. ISBN: 9781420082036.

Compulsory for: WUBNTBSc Minor Bionanotechnology2MO