|Teaching method||Contact hours|
|Course coordinator(s)||dr. O Madsen|
|Lecturer(s)||dr. ir. HJ Megens|
|prof. dr. MAM Groenen|
|dr. O Madsen|
|dr. JAL van Kan|
|prof. dr. ME Schranz|
|Examiner(s)||dr. O Madsen|
|prof. dr. MAM Groenen|
Language of instruction:
Assumed knowledge on:
Basic knowledge on molecular biology and genetics, such as given in GEN-11806 Fundamentals in Genetics, or courses such as BIC-10306 Practical Biological Chemistry or MOB-20306 Gene Technology.
Note: This course has a maximum number of participants. The deadline for registration is one week earlier than usual.
See Academic Year.(http://www.wur.nl/en/Education-Programmes/Current-Students/Agenda-Calendar-Academic-Year.htm) -> Registration for Courses.
The course discusses the structure and function of genomes of organisms from all kingdoms. The topics that are treated cover:
- chromosome structure and topology;
- genome sequencing, genome assembly and functional annotation;
- whole genome sequence analysis; genome synteny and evolution;
- transcriptome analysis by RNA-seq; protein-protein interactions and proteomics; epigenomics
- functional genome analysis;
- variation in genomes.
After successful completion of this course students are expected to be able to:
- retrieve and describe information from genomic databases
- describe genome analysis strategies related to genome assembly, annotation, and functional genomics
- describe and explain organization, function and evolution of genomes
- contrast features of genomes of different domains of life, and compare genomes of different species.
- apply and assess tools for genome analysis.
- interpret complex data and analysis results derived from complex biological systems.
- judge the merits of results and interpretations based on known strengths and weaknesses of data sources and analysis strategies.
- integrate results obtained from literature/research project
The final grade is based on a written examination and the assessment of a literature/research project during the last two weeks of the course.
The contents of the computer exercises are available in Brightspace. Additional material in Brightspace consists of links to relevant websites, to the Powerpoint presentations of the lectures and to further background information in review papers. Literature for the research/literature project is accessible from literature databases and journal home pages.
|Compulsory for:||WUEPS||BSc Minor Experimental Plant Sciences||5AF|
|WUPBT||BSc Minor Plant Biotechnology||2AF|