CBI-10806 Introduction to Cell Biology

Course

Credits 6.00

Teaching methodContact hours
Lecture12
Tutorial9
Practical30
Group work12
Independent study0
Course coordinator(s)dr. R Tennekes
Lecturer(s)prof. dr. D Weijers
dr. ir. HS van der Honing
dr. R Tennekes
Examiner(s)dr. R Tennekes

Language of instruction:

EN

Mandatory knowledge:

ZSS06100 Laboratory Safety

Assumed knowledge on:

Middle School Biology. If this knowledge has not been obtained, please prepare by reading the first two chapters of the book: Essential Cell Biology. Keeping up with the course content is key!

Continuation courses:

The course content is used in other first year courses. Second and third year courses that follow are e.g. CBI20306.

Contents:

The course Introduction to Cell Biology forms an introductory and partly specialized course into the structure and function of cells, its organelles and biomolecules.
Special focus is directed to the molecular and biochemical basis of cell function, ultrastructure and function of the different cell organelles, the cytoskeleton and cellular organization and to cell differentiation processes. Basic principles of intra- and extracellular communication processes will be studied to obtain insight into the regulation of cell function in the context of whole tissues, organs and complete organisms.
The basic knowledge obtained should provide a solid basis for several more specialized courses in the first year. Results of research into cellular mechanisms are extensively applied in practice. Examples are the recent developments in the fields of biochemistry and gene technology for diagnosis, vaccination, medication, biological pest control and genetic selection.

Learning outcomes:

After successful completion of this course students are expected to be able to:
- explain the structure and components of pro- and eukaryotic cells, especially macromolecules, cell organelles, membranes and cytoskeleton;
- explain the molecular principles of DNA replication, transcription, RNA translation, and protein formation;
- explain the cell cycle, its regulation and mitosis and meiosis;
- explain the way cells communicate with each other, and how this results in regulation of cell function and cell differentiation;
- basic principles of light- and electron-microscopy;
- basic cell biological assays.


Activities:

Every week is started with a new theme. This is introduced during plenary lectures on Mondays. Subsequently students work independently (with or without supervision) on ICT modules, case studies and learning objectives. Cases should challenge the students to use the obtained knowledge of the week to resolve different cases. The learning objectives comprise the knowledge needed to understand and explain the case. The first step in writing is writing in your own words and using the scientific terms appropriately, this is practiced with the learning objectives each week wherein students write a short summary of each learning objective (which is also a good overview of the required knowledge each week). The week is finalized with a mandatory self-assessment which can result in bonuspoints that will be added to the exam result.
Laboratory practicals are a mandatory part of the course. Subjects chosen are related to the cases under study. Techniques applied are microscopy and cell biological analyses/assays and are supported by computer modules and films.

Examination:

Practical training is compulsory. Each self-assessment can lead to bonuspoints that are added to the exam result (maximum of 0.5 bonus, valid during the 3 exams of this course year). The final exam is computer based and comprises 90 multiple choice questions that cover the theoretical and practical learning outcomes of the course. A minimum mark of 5.5 is required.

Literature:

For this course, the book: Alberts, B. (2019). Essential cell biology. New York, N.Y.,US: Garland Science. 5th edition . ISBN 978-0-393-68039-3 is used.
A Brightspace environment is available with specific literature, ICT modules, movies and PowerPoint presentations of the lectures.
The practical manual CBI-10806 for this course and book are for sale at the Study Store.

ProgrammePhaseSpecializationPeriod
Compulsory for: BASAnimal SciencesBSc1MO
BFTFood TechnologyBSc1MO