HNE-31903 Randomised Controlled Trials: design and analysis (DL)


Credits 3.00

Teaching methodContact hours
Individual Paper1
Distance Knowledge clip
Distance Tutorial3
Distance E-learning material
Course coordinator(s)dr. ir. AM Berendsen
dr. ir. MC Busstra
Lecturer(s)dr. ir. NM de Roos
Examiner(s)dr. ir. NM de Roos

Language of instruction:


Assumed knowledge on:

DL-introduction in analytical epidemiology; DL-integration of evidence 1

Continuation courses:

The DL-MSc-specializations have a fixed schedule during the pilot-phase


NOTE: this course is taught specifically for the students in Distance Learning Specialization and is not available in academic year 2015/2016 for the on-Campus students. Self-registration for this course is not possible.

This course focuses on the methodological issues in designing an experimental study: how to obtain an appropriate sample size and how to perform statistical analysis of data derived from randomized controlled trials.

Learning outcomes:

After successful completion of this course students are expected to be able to: - formulate a good research question;
- evaluate the validity and precision of a parallel arm post-test only, parallel arm pre-test post-test, and cross-over design;
- perform appropriate sample size calculations for different study designs;
- choose and conduct the appropriate method of data analysis of randomized controlled trials, given the study design and type of variables.


Studying knowledge clips, studying e-modules, individual assignment, and individual assignment with peer-review.


Will be announced.


Petrie & Sabin, Medical statistics at a glance, chapters 9, 13, 20, 21, 22, 24, 41.

Compulsory for: MNHNutrition and HealthMScE: Nutritional Epidemiology and Public Health6DL